Endocrine Abstracts

The causes of panhypopituitarism are well known and pituitary metastases is a recognised but rare cause. It can often be difficult to diagnose because the non-specific features of malignancy mask those of pituitary involvement.We present the case of a 73 year old gentleman who complained of fatigue and weight loss. He had recently been treated for a radiographically proven bronchopneumonia. Endocrine checks suggested secondary hypothyroidism however (TSH...

Hypopituitarism due to neurosarcoidosis is mainly seen in patients with extensive systemic disease. However, pituitary involvement can occur without other classical features of the disease, as illustrated by the following cases.Case 1: An Afro-Caribbean male presented in 1986 with failure of pubertal development aged 22. Initial investigations demonstrated hypothalamic hypogonadism, secondary hypothyroidism and a suboptimal cortisol response to hypoglyca...